Synthesis of chiral amines using redox biocatalysis

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

synthesis of amido alkylnaphthols using nano-magnetic particles and surfactants

we used dbsa and nano-magnetic for the synthesis of amido alkylnaphtols.

15 صفحه اول

Tools in Biocatalysis Enzyme Immobilisation on Silica and Synthesis of Enantiopure Amines

This thesis presents two techniques in the field of biocatalysis: An enzyme immobilisation method based on the His6-tag for attachment on modified silica oxide beads, and it’s employment in aqueous and organic medium for synthesis applications. The method functions as a one step extraction and immobilisation protocol. An equilibrium displacement system which enables complete conversion in react...

متن کامل

Asymmetric synthesis of substituted NH-piperidines from chiral amines.

Previously, we reported an efficient asymmetric synthesis of substituted piperidines through an exocyclic chirality induced nitroalkene/amine/enone (NAE) condensation reaction. An effective protecting group strategy was developed herein to achieve enantiopure piperidines (yields up to 92%) with complete chirality retention (ee > 95%). A simple derivatization of the obtained piperidines gave thi...

متن کامل

Nucleophilic chiral amines as catalysts in asymmetric synthesis.

2.1. Kinetic Resolution of Alcohols and Amines 2987 2.2. Ketene Acylation 2995 2.3. Cycloadditions 2996 2.3.1. â-Lactone Formation 2996 2.3.2. â-Lactam Formation 2997 2.3.3. Ketene Dimerization 2999 2.4. Halogenation 3000 2.5. Baylis−Hillman Reactions 3000 2.6. Desymmetrization of Cyclic Anhydrides 3002 2.7. C-Acylation 3004 2.8. Cyanation 3004 3. Solid Phase Chemistry 3007 3.1. Solution Cataly...

متن کامل

ARTICLE Necessary and Sufficient Conditions for the Asymmetric Synthesis of Chiral Amines Using v-Aminotransferases

The half reactions of v-aminotransferase (vAT) from Vibrio fluvialis JS17 (v-ATVf) were carried out using purified pyridoxal 50-phosphate-enzyme (PLP-Enz) and pyridoxamine 50-phosphate-enzyme (PMP-Enz) complexes to investigate the relative activities of substrates. In the reaction generating PMP-Enz from PLP-Enz using Lalanine as an amine donor, L-alanine showed about 70% of the initial reactio...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Current Opinion in Chemical Biology

سال: 2018

ISSN: 1367-5931

DOI: 10.1016/j.cbpa.2017.09.008